ISAR SUMMIT

Probucol for Optimal Drug Release

Probucol obviates the Polymer related side effects of Acute Thrombogenicity, Inflammation, Delayed arterial healing.

Due to its high lipophilicity it facilitates retardation of Everolimus release in similar manner to that achieved by polymers.

Probucol and Everolimus co-release upto 80% in 28 days.*

Probucol is a well studied drug at a much higher does (upto 500 mg) oral dosage with proven safety.